What is UKBOR?
The UK National Barrett’s Registry (UKBOR) is a database which contains information on many thousands of patients with Barrett’s Oesophagus, registered by Gastroenterologists throughout the UK. The Registry was established in 1996 as a joint initiative of the Oesophageal Section of the British Society of Gastroenterology and the European Cancer Prevention Organisation. The stimulus for this was the rapidly increasing incidence of adenocarcinoma (AC) of the oesophagus, now ten times more common than it was 30 years ago. Whilst Barrett’s Oesophagus is the predominant precursor lesion, only a small proportion of Barrett’s patients (less than 10%) will develop AC and aim the of UKBOR was to facilitate studies on the characteristics of patients with Barrett’s, the natural history of the condition, which patients are at greatest risk of AC development and therefore need closest follow up and the effect of various treatments for Barrett’s including pharmacological, endoscopic and surgical treatments. Because it is difficult for individual groups of researchers to conduct these studies due to the small numbers of Barrett’s patients seen in individual centres, it was felt that the way forward was that followed in the case of other relatively uncommon yet important conditions of establishing a national database of cases registered by motivated Gastroenterologists.